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The most comprehensive study of neurodevelopmental conditions in Kenya and South Africa ever conducted shares preliminary results and lessons.
The drug, welcomed by patients, might be just the first of many.
The map diagrams more than half a million neuronal connections in the first complete connectome of Drosophila and holds clues about which brain architectures best support learning.
The proteins are part of a newly discovered complex that mends genetic damage exclusively in neurons.
The new tool may pose challenges for the scientific community, but used wisely, it can help researchers save time and resources.
The two journals, although differing in initial support, both realized the need for a publication focused exclusively on the neurodiverse experience.
Both human and mouse progenitor cells with the alterations struggle to become neurons and instead express genes that are typically active only in muscle or the heart. The post Autism-linked MYT1L mutations prompt ‘identity crisis’ in budding brain cells appeared first on Spectrum | Autism Research News.
The approach removes methyl tags from the gene and shields it from other silencing factors without changing the gene itself, raising hopes for a new treatment. The post Epigenome edits unmute MECP2 in Rett-like neurons appeared first on Spectrum | Autism Research News.
FMR1 loss impairs sodium channels, hindering mouse neurons from generating the electrical signals needed to transmit information. The post Neurons struggle to spike without fragile X gene appeared first on Spectrum | Autism Research News.
After a year of intense growth, funding for biotech is in decline. The result is layoffs and program cuts — and maybe some innovation.
Connections between 13 autism-linked proteins and their binding partners in excitatory neurons implicate a new molecular pathway. The post Fishing for protein partners nets clues to autism appeared first on Spectrum | Autism Research News.
The finding calls into question differences between autistic and non-autistic people on a decades-old theory-of-mind test involving interacting geometric shapes.
Early treatment with nutritional supplements and a high-protein diet forestalls some neurodevelopmental problems for children with BCKDK deficiency.
Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene. The post Chromatin remodeling tied to altered splicing in autism model appeared first on Spectrum | Autism Research News.
Five autism-linked genes widely known as chromatin regulators appear to also shape the cell’s internal skeleton. The post Autism-linked chromatin regulators may moonlight as microtubule influencers appeared first on Spectrum | Autism Research News.
FMR1 loss impairs sodium channels, hindering mouse neurons from generating the electrical signals needed to transmit information.
The approach removes methyl tags from the gene and shields it from other silencing factors without changing the gene itself, raising hopes for a new treatment.
A new measure shows how greatly movement influences associations between traits and brain activity, revealing abundant false positives and false negatives. The post Head motion mars most fMRI results, even after correction appeared first on Spectrum | Autism Research News.
Both human and mouse progenitor cells with the alterations struggle to become neurons and instead express genes that are typically active only in muscle or the heart.
Elsevier’s retractions focus on peer review and conflicts of interest. The post Prolific autism researcher has two dozen papers retracted appeared first on Spectrum | Autism Research News.
The findings put genetic background forward to help explain autism’s heterogeneity. The post CHD8 mutation in 33 mouse strains yields range of traits appeared first on Spectrum | Autism Research News.
Serious differences in autism identification persist, according to an analysis of autistic children in New Jersey over 16 years. The post Racial, economic disparities skew New Jersey data on autism, intellectual disability appeared first on Spectrum | Autism Research News.
Five autism-linked genes widely known as chromatin regulators appear to also shape the cell’s internal skeleton.
Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.
CRISPR-edited prairie voles that lack receptors for the so-called “social hormone” still bond with their mate and pups, raising questions about the molecule’s role. The post ‘Mind-blowing’ study upends conventional wisdom on oxytocin appeared first on Spectrum | Autism Research News.
Connections between 13 autism-linked proteins and their binding partners in excitatory neurons implicate a new molecular pathway.
To include more autistic people in research, here's what scientists need to know about informed consent procedures for study participants who have impaired decision-making capacity. The post Decisional capacity and informed consent, explained appeared first on Spectrum | Autism Research News.
The findings put genetic background forward to help explain autism’s heterogeneity.
Elsevier’s retractions focus on peer review and conflicts of interest.
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane. The post Mutations in autism-linked gene cause membrane mischief appeared first on Spectrum | Autism Research News.
